G&T Brighten Peels

Long-term nasal and peri-oral tightening by a single fractional non-insulated micro-needle radiofrequency treatment by Yohei Tanaka, MD, PhD

Study Overview

Yohei Tanaka, MD, PhD has recently investigated the effectiveness of a single ENDYMED INTENSIF treatment in delivering long lasting nasal and peri-oral tightening.

Deep nasolabial folds, perioral wrinkles and loss of skin laxity to the lower two-thirds of the face are a significant sign of ageing and are therefore a key aspect in facial rejuvenation. The major cause of this facial skin ageing is the loss of collagen.

ENDYMED radiofrequency treatments are clinically proven to deliver long-lasting skin tightening results through stimulating collagen and elastin production in the dermis and hypodermis. The effects of this on the nasal and peri-oral area were closely examined.

In the clinical study fifteen Asian patients underwent one full face ENDYMED INTENSIF. During this clinically advanced treatment, radiofrequency is delivered three layers deep into the skin using unique, non-insulated gold needles and fractionated pulse mode technology, creating fractional columns of coagulation and volumetric heating to a controlled depth of up to 5.0mm. This kick-starts the rejuvenation of the skin by stimulating the production of collagen, hyaluronic acid and other key components of the extra-cellular matrix, while also increasing epidermal cell renewal. Treatments were delivered using ENDYMED’s advanced predetermined settings, with multiple passes being performed on the treatment area.

The effectiveness of treatments for long-term nasal and peri-oral tightening was measured using three dimensional assessments to obtain objective volumetric evaluations. Results saw a significant and long-lasting volumetric reduction in the nasal and peri-oral area, indicating significant skin tightening effects, as well as an improvement in skin texture and dilated skin pores.

The significant tightening effects on the lower two thirds of the face as well as the cheeks, nasal and peri-oral areas, lasted for a minimum of 12 months in all patients. After a 12 month assessment 100% of patients were satisfied with their results and no side effects were reported.

Clinically proven results





Working with AesthetiCare

With advanced, clinically proven technologies and excellent client satisfaction, ENDYMED is a fantastic, unique addition to your skincare offering. When you become an ENDYMED Partner, we provide you with all the support you need to make ENDYMED a success in your business. From professional in-clinic training and a fabulous launch, to your Marketing Toolkit, packed full of email and social media content, imagery, treatment videos and top tips for a successful launch.

We’ll also make sure you get the ongoing support you need with our professional customer services team and your dedicated account manager.

We’d love to give you a free demonstration and talk you through the ENDYMED technology and how it can fit into your business. Simply complete the contact form at the bottom of the page or call 0800 0195 322 and we’ll be in touch as soon as we can.

Request a call back

To request a call back to discuss how you can offer ENDYMED treatments  in your clinic or to arrange a FREE no obligation demonstration, please enter your details into the form below, stating the most convenient time to call and we will be in touch as soon as we can:

Your name (required)

Name of clinic (required)

Your telephone number (required)

Your email (required)

What day is most convenient for us to call you on?


What time is most convenient for us to call you on?



I am happy for AesthetiCare to contact me regarding AesthetiCare products and services:

By PhoneBy EmailBy Mail

Please enter the following text