G&T Brighten Peels

The Mechanisms and Potential Impact of Stem Cell Activation in Skin Rejuvenation

Study Overview

All life on earth, whether human, animal or plant, is formed using stem cells. Their unique ability to differentiate whichever cell is required means they are vital to many of the body’s most important processes, including skin rejuvenation. As you age, stem cell activity in the skin declines, meaning they produce fewer fibroblasts which means the skin looks less vibrant and loses its elasticity and firmness.

However, recent clinical studies have shown that proteins extracted from the embryos of the scientific snail Cryptomphalus Aspersa (CAF BioAction), as found in all Endocare CELLPRO products, have the ability to affect the signalling pathways of Stem Cells found within the human epidermis. This means it is the first clinically proven programme to actually activate the skin’s own stem cells and thus has the potential to address root causes of skin ageing, and achieve true skin restoration and regeneration.”

When looking at human skin stem cells taken from the hair follicle bulge, the studies found that CAF BioAction was able to “induce differentiation of mesenchymal stem cells to cutaneous keratinocyte and fibroblast cell lines” whilst also inducing the “migration of keratinocytes and fibroblasts in a time and dose-dependent manner.

In other words, Endocare CELLPRO’s CAF BioAction extract was clinically proven to activate the skin’s existing stem cells, causing them to differentiate into fibroblasts and keratinocytes, improving tissue repair and reducing the age-related changes to the cells themselves. Fibroblasts are the key to skin rejuvenation, creating collagen, elastin and natural skin hydrators, leaving the skin appearing smoother, brighter and tighter – it’s the cell that we target with almost every in-clinic rejuvenation treatment.

Not all Stem Cell products work in the same way. The remarkable growth in interest in Stem Cell skin products has meant many products have appeared on the market claiming to be “stem cell” treatments utilising secretions harvested from human or plant stem cells and aimed at improving the appearance of ageing skin. Whilst these products do have varying effects on the skin, they do not affect the stem cells themselves. Only Endocare CELLPRO is clinically proven to activate the skins existing stem cells and haven a significant effect on the visible signs of skin ageing.

Clinically proven results


The Endocare Programme provides the ultimate skin rejuvenation combination, bringing together the latest innovations in stem cell activators and growth factors, with technologies you know and trust such as Vitamin A and C.

The unique Endocare rejuvenation programme combines the very first stem cell activator with concentrated growth factors. This unrivalled technology has been researched and developed by clinical skin scientists and dermatologists across the globe.

The Endocare Programme combines Endocare CELLPRO and Concentrate Serums in an easy-to-follow daily regime, changing the way your skin works to significantly improve:

  • Skin Elasticity, Plumpness & Tightness

  • Fine Lines & Wrinkles

  • Texture & Tone

  • Skin Brightness

It’s the advanced skin biotechnologies derived from the scientific snail, Cryptomphalus Aspersa, and high-level research, development and clinical data that makes the Endocare Programme special.

CAF BioAction is the very first stem cell activation biotechnology, and is the basis to every Endocare CELLPRO product. Derived from the embryo of the scientific snail, CAF BioAction reinvigorates your own skin stem cells to generate new fibroblasts – the key to skin rejuvenation. These fibroblasts produce new collagen and hyaluronic acid, changing your skin from withinEndocare CELLPRO also features a patented and advanced combination of Vitamin A ingredients, further activating the skin’s natural processes.

SCA BioRepair is the original skin biotechnology derived from the scientific snail. This intense growth factor complex targets your existing fibroblasts to make them work harder and produce even more new collagen and hyaluronic acid. There are two Endocare Concentrate Serums, each containing high levels of SCA BioRepair:

  • Endocare C PURE Concentrate – boosted with an advanced combination of Vitamin C to strengthen and protect new collagen

  • Endocare Tensage Concentrate – boosted with Calcium to stimulate the production of collagen and other skin firming fibres

The high-intensity Endocare Programme

The Endocare Programme consists of daily stem cell activation, combined with periods of high-intensity growth factor stimulation – using the latest innovations in skincare doesn’t have to be complicated!

Your daily stem cell activation regime involves just three Endocare CELLPRO products. Every other month this is combined with high-intensity growth factor stimulation with the nightly use of an Endocare Concentrate serum – simply alternate between the two serums throughout the year for maximum impact.

Endocare CELLPRO Gelcream

A light, creamy gel that leaves skin feeling hydrated but dry to the touch – perfect for use in the morning. It combines high levels of CAF BioAction Technology with RetinSphere Technology, not to mention ingredients that enhance skin architecture, moisturisers and Vitamins C and E.

Endocare CELLPRO Intensive Eye Contour

A light, hydrating cream specifically designed to target signs of ageing around the eye with key Endocare CELLPRO technologies and CAF BioAction Technology, plus caffeine and haloxyl to increase circulation and reduce puffiness.

Endocare CELLPRO Cream

A rich, non-oily cream with an advanced moisturising system that leaves skin feeling intensely hydrated, so it’s ideal to use as a night cream. Endocare CELLPRO Cream also contains optimum levels of CAF BioAction Technology, RetinShpere Technology, Vitamins C and E and skin architecture enhancing ingredients.

Endocare Tensage Concentrate Serum

This intensely rejuvenating Growth Factor serum is boosted with Calcium for increased collagen production and contains intensive skin moisturisers and skin brightening ingredients.

Endocare C PURE Concentrate Serum

Advanced Growth Factor technology is mixed with high concentrations of an advanced combination of Vitamin C to provide increased levels of skin protection and brightness.

Working with AesthetiCare

With advanced, clinically proven technologies and excellent client satisfaction, Endocare is a fantastic, unique addition to your skincare offering. When you become an Endocare Partner, we provide you with all the support you need to make Endocare a success in your business. From professional in-clinic training to your Marketing Toolkit, packed full of email and social media content, imagery and top tips for a successful launch.

We’ll also make sure you get the ongoing support you need with our professional customer services team and your dedicated account manager.

What’s more, our exclusive introductory offer gives you enough stock of every product in the Endocare range to get up and running immediately with a huge overall discount of more than 25%!

We’d love to talk you through the Endocare regime and how it can fit into your business. Simply complete the contact form at the bottom of the page or call 0800 0195 322 and we’ll be in touch as soon as we can.

Request a call back

To request a call back to discuss how you can stock Endocare  in your clinic or to arrange a FREE no obligation visit, please enter your details into the form below, stating the most convenient time to call and we will be in touch as soon as we can:

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